RESEARCHER PROFILE
Assoc Professor Cedric Bardy, SAHMRI (2023)
Director of The Laboratory for Human Neurophysiology, Genetics & Stem Cells
South Australian Health and Medical Research Institute (SAHMRI) &
Professor, Flinders University
Adelaide, South Australia
Filmed November 2023
Associate Professor Cedric Bardy is the Director of The Laboratory for Human Neurophysiology, Genetics & Stem Cells, located at SAHMRI. South Australia.
His current research uses preclinical, patient-derived cell models to test innovative therapeutic strategies, with a current focus on Parkinson’s disease, brain cancer and childhood dementia (Sanfilippo syndrome).
His work has established a platform to facilitate the discovery and validation of treatments for brain disorders. Their research is at the frontier of human cellular neuroscience research and translational applications that benefit global public health.
In particular, Cedric is the inventor of BrainPhys; a neuronal medium broadly used to culture human neurons in vitro, commercialised by STEMCELL Technologies.
The ability to grow human brain cells in a petri dish opens up new possibilities for research and discovery in neuroscience.
The BrainPhys medium allows human brain cells to function as they would in the adult human brain, revolutionizing research in labs across the world.
Cedric Bardy’s research enables researchers to study human brain disorders in a more physiological context, potentially leading to new treatments for brain cancer, Parkinson’s disease, and Sanfilippo Syndrome.
Cedric Bardy’s international journey from France to Canada to Australia and then to the United States showcases the global nature of scientific research and collaboration.
The passion for neuroscience stems from the fact that everything we care about as humans is influenced by brain activity.
Cedric Bardy is passionate about finding ways to treat the brain when things go wrong, showing a deep commitment to neurological research.
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Next-generation NK cell-based immunotherapies for hard-to-treat cancers
Associate Professor Fernando Guimaraes is an internationally recognised leader in cancer immunotherapy and natural killer (NK) cell biology. Based at The University of Queensland, he leads innovative research focused on developing next-generation NK cell-based immunotherapies for hard-to-treat cancers, including sarcomas and neuroblastoma.
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Metabolic phenotyping, lipidomics & bioinformatics in dementia
Dr Luke Whiley is a dementia researcher whose work focuses on understanding how the body’s metabolism, particularly the biology of fats known as lipids, influences our health throughout ageing.
His research explores how the body responds to illness, lifestyle, and environmental stress at a chemical level, and how these responses shape longterm disease risk. Using advanced blood-based measurement technologies, Dr Whiley studies thousands of small molecules at once to build a snapshot of a person’s metabolic health. By combining these measurements with data science approaches, his work identifies biological pathways that become disrupted in disease, providing insight into why some people are more vulnerable to conditions such as dementia.
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Systems genetics to determine risk of developing diabetes complications
Professor Morahan invented the term “Systems Genetics” for the science field that examines how genetic variants can affect whole networks of genes and whole systems; there are now several laboratories and institutes of systems genetics around the world. He also developed the next-generation genetic resource, The Gene Mine, the most powerful of its type in the world, used globally in rapid mapping and identification of genes. Collaborators nationally and internationally have tested The Gene Mine for traits and diseases in which they specialise.
