DE-PRESCRIBING MEDICATIONS IN OLDER ADULTS WITH DEMENTIA
Dr Daniel Hoyle
Senior Lecturer, Therapeutics and Pharmacy Practice
School of Pharmacy and Pharmacology,
University of Tasmania, Australia
RESEARCHER PROFILE
Filmed in Hobart, Tasmania, Australia | January 2025
Dr. Daniel Hoyle is a Senior Lecturer in Therapeutics and Pharmacy Practice at the School of Pharmacy and Pharmacology, University of Tasmania. He is also an experienced clinical pharmacist with expertise in medication management in older people. Dr. Hoyle’s research interests focus on improving medicine use in older people with dementia.
He earned his PhD from the University of Tasmania in 2020, where his doctoral research examined the clinical and economic outcomes of psychotropic deprescribing within the multidisciplinary “Reducing Use of Sedatives” project implemented across 150 Australian aged care homes. This research has received several accolades, including First Place in the International Psychogeriatric Association Junior Research Awards in 2019.
Currently, Dr. Hoyle leads several projects, including research aimed at improving anticoagulant use in older individuals with dementia and atrial fibrillation using national primary care provider datasets, and the implementation of a hospital-based antipsychotic stewardship program for patients with dementia and/or delirium.
A current project is Geriatric Antipsychotic Stewardship (GApS) Program for Behavioural and Psychological Symptoms of Dementia and Delirium. This program is funded by the Royal Hobart Hospital Research Foundation through an Incubator Grant.
Additionally, Dr. Hoyle serves as an investigator within an educational intervention aimed at improving anticholinergic prescribing in hospitals. Dr. Hoyle is a guest editor with Pharmacy MDPI and holds elected positions on the Australian Deprescribing Network Executive Committee and the Pharmaceutical Society of Australia’s Tasmanian Branch Committee.
https://orcid.org/0000-0003-2867-3736
-
Neonatal respiratory trials in sick & preterm newborn infants
Prof Brett J. Manley leads and collaborates on large national and international randomised clinical trials in neonatology. He previously collaborated on 4 randomised trials of nasal high-flow as non-invasive respiratory support for preterm and term infants, all of which were published in N Engl J Med. Recently he led the PLUSS trial of intratracheal budesonide for extremely preterm infants, that recruited in 21 NICUs across 4 countries, the results of which were published in JAMA. PLUSS was awarded the Australian Clinical Trials Alliance Trial of the Year in 2025. Another passion of his is mentoring and supervising early career researchers to undertake their own clinical trials.
-
Stem cells used for age-related macular degeneration
Dr. Jenna Hall is a passionate and accomplished biologist with expertise in induced pluripotent stem cell (iPSC) culture, disease modelling, and high-throughput automated systems. She recently earned her PhD from the University of Melbourne, where her research focused on using iPSC-derived retinal pigment epithelium (RPE) cells to study age-related macular degeneration. Dr Hall’s technical skillset spans manual and automated cell reprogramming and differentiation, quantitative microscopy-based phenotyping, and large scale -omics analysis.
-
Neuroscience, neuropharmacology and exercise science
Dr Jacob Thorstensen is an early-career Assistant Professor in Neuroscience and Physiology in the Faculty of Health Sciences & Medicine at Bond University. He is also an honorary research fellow in The School of Biomedical Sciences at The University of Queensland. His work has unveiled several new neuroscientific mechanisms which have future applications for movement disorders.
