TRANSFORMING CLINICAL CARE: IMPACT OF LEUKAEMIA FOUNDATION’S RESEARCH FUNDING INTO BLOOD CANCER
With
Bill Stavreski, Head of Research
Leukaemia Foundation, Australia
RESEARCH IMPACT
Filmed in Melbourne | May 2025
Released to coincide with World Blood Cancer Day 2025
The Leukaemia Foundation is committed to funding research innovations that drive advancements in new diagnostics, treatments and novel therapies, supporting the careers of promising scientists and clinicians and giving Australians access to global clinical trials.
The Leukaemia Foundation state there are over 120 different types of blood cancer and all of which the Foundation provides support to people.
Bill Stavreski is the Head of Research at the Leukaemia Foundation who talks about the research impact in recent years. The Foundation itself marks its 25th anniversary in 2025, having funded a wide range of health and medical research since 2000. With a focus on basic science, health services research, treatment, and care, the organisation has invested nearly $90 million (adjusted in current dollars terms) in approximately 370 research grants over the years.
The Foundation primarily relies on the generosity of public donations, with no government funding. This funding has led to significant advancements in clinical practice, including a groundbreaking diagnostic test now available across Australia, significantly easing the financial burden on patients.
One notable achievement includes the first successful growth of leukaemic cells in a dish, facilitating advancements in treatment testing. Additionally, the Foundation established a pioneering genomic screening program for patients with hard-to-treat blood cancers, significantly improving the chances of finding effective treatments.
Through this work, the Foundation underscores that research is centred on people, aiming to transform lives and support families affected by blood cancer.
Source: Adapted from the Leukaemia Foundation website and transcript
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Relationship between language-literacy skills and mental health
In an innovative move towards enhancing mental health services, Associate Professor Amanda Neil and team, supported by the RHH Research Foundation, are undertaking a crucial study on language-literacy skills of patients within mental health care settings. This year-long project, which commenced in April 2024, seeks to unravel to what extent, where and for whom language-literacy skills are being considered in Tasmanian mental health service provision.
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Targeting chemotherapy resistance in ovarian cancer patients
Dr Alex Cole, from the Centenary Institute’s Centre for Biomedical AI, is now leading the research focused on developing a new treatment to counteract a protein called follistatin (FST), known for making ovarian cancer cells resistant to chemotherapy.
By employing cutting-edge molecular biology and directed evolution techniques, the project aims to create nanobodies—small, precise molecules—that can block FST. If successful, these nanobodies could enhance the effectiveness of chemotherapy and improve ovarian cancer treatment rates.
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Benefits of prehabilitation ahead of surgery
Dr Matthew Wallen PhD, AES, AEP is a Senior Research Fellow in Cancer Survivorship, the Deputy Lead of the Cancer Survivorship Program, and a Senior Lecturer in Exercise Science and Clinical Exercise Physiology within the College of Nursing and Health Sciences at Flinders University, in South Australia. His clinical interest focuses on improving outcomes for people requiring major surgery, specifically (1) lifestyle interventions, including exercise, nutritional, and psychological support to improve the health and wellbeing of people prior to surgery, termed ‘prehabilitation’, (2) novel physical function assessments aimed at identifying people at risk of treatment-related complications, and (3) implementation of new models of care in cancer.
