LIVER CANCER & PATIENT-DERIVED TUMOUR ORGANOIDS
With
Dr Benjamin Dwyer,
Senior Research Fellow &
Director, Western Australian Organioid Innovation Hub,
Curtin Medical Research Institute,
Curtin University, Western Australia
RESEARCHER PROFILE
Filmed in Perth, Western Australia | February 2026
Dr Benjamin Dwyer is a translational cancer researcher driven by a clear purpose: to ensure discoveries made in the laboratory genuinely improve outcomes for patients.
Based at Curtin University, he established and now leads the organoid platform within the Liver Cancer Collaborative and directs the WA Organoid Innovation Hub, working at the intersection of biology, medicine and biotechnology to accelerate new treatments for liver cancer.
After completing his PhD in Perth, Dr Dwyer joined the world-leading liver research group of Prof Stuart Forbes at the University of Edinburgh, where he contributed to research spanning fundamental biology, clinical trials and commercial translation. He helped define how cholangiocarcinoma crosstalk with macrophages establishes a protective environment. In parallel, he was closely involved in the development of macrophage cell therapy for cirrhosis as part of the management team of the MATCH trials, and established novel, GMP-compatible methods to engineer and cryopreserve therapeutic macrophages, foundational methods for the commercial development of macrophage therapy. He was part of the founding team of a biotechnology spinout created to translate this work, and the therapeutic strategy built on those early methods is now progressing through Phase 1 clinical testing. Seeing principles he helped establish move from bench to bedside has been a defining milestone in his career.
Today, as part of the Liver Cancer Collaborative his research focuses on building patient-derived “mini tumours” for drug development that better predict treatment response, narrowing the gap between laboratory models and real patient outcomes.
COLLABORATIONS WITH:
Perkins Cancer Biobank, Australian Centre for RNA Therapeutics in Cancer, UWA, WA Data Science Innovation Hub, Murdoch University, Epichem, Cholangiocarcinoma Foundation Australia WEHI National Drug Discovery Centre, Inventia Life Sciences, University of Edinburgh, Scottish National Blood Transfusion Service (SNBTS), University of Calgary
FUNDING FROM:
Department of Health WA FHRI Fund, Cancer Research Trust, Gastroenterological Society of Australia (GESA), Ian Potter Foundation, AMMF- The Cholangiocarcinoma Charity,
Source: Supplied and adapted
https://orcid.org/0000-0003-2527-5417
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Vaccine effectiveness against infections triggering autoimmune disease
Dr Deborah Burnett is a Scientia Senior Lecturer and Laboratory Head at UNSW, where she leads a multidisciplinary research program spanning mechanistic immunology and translational vaccinology. Her work focuses on understanding how immune responses can protect against challenging infectious threats, including bacterial infections and infections associated with autoimmune disease.
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Personalised approaches to lung therapy
Dr. Adams’ research focus is on lung cancer, which is the deadliest of all cancers worldwide. He is working towards developing personalised approaches to pinpoint a therapy that is going to be most effective for the person with that disease. Dr. Adams’ research is focusing on chemotherapy and targeted therapy, and he is trying to identify upfront which of those tumours are likely to be resistant to the therapy. He then identifies strategies that will resensitize or increase the sensitivity of the tumour to the standard of care that is targeted therapy or chemotherapy.
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Using Gut Microbes to Reduce Blood Pressure
Professor Francine Marques is an National Health and Medical Research Council Emerging Leader, Viertel Charitable Foundation, and National Heart Foundation Fellow.
She leads the Hypertension Research Laboratory at Monash University and has published more than 120 peer-reviewed papers in journals such as Nature Reviews Cardiology, Nature Medicine, Nature Cardiovascular Research, and Circulation.
