HYPERTENSION AND THE GUT MICROBIOME: USING GUT MICROBES TO REDUCE BLOOD PRESSURE
Professor Francine Marques
Professor of Genetics and Genomics
Monash University, Victoria, Australia
RESEARCHER PROFILE (Filmed in Clayton, Victoria | December 2024)
Professor Francine Marques is an National Health and Medical Research Council Emerging Leader, Viertel Charitable Foundation, and National Heart Foundation Fellow.
She leads the Hypertension Research Laboratory at Monash University and has published more than 120 peer-reviewed papers in journals such as Nature Reviews Cardiology, Nature Medicine, Nature Cardiovascular Research, and Circulation.
As a researcher Professor Marques has secured over $10 million in competitive funding as a principal investigator. She has won 31 awards, including the 2019 American Heart Association Hypertension Council Goldblatt Award, the 2020 High Blood Pressure Research Council of Australia and 2021 International Society of Hypertension Mid-Career Awards, the 2021 Australian Academy of Science Gottschalk Medal, and the 2024 Australian Society of Medical Research Peter Doherty Leading Light Award, and was a finalist for 12 awards, including the Eureka Prize Emerging Leader in Science.
Her research team aims to build exceptional scientists that help improve cardiovascular health, using translational approaches to lower blood pressure via the gut microbiome. Professor Marques is also passionate about equity, diversity and inclusion (EDI) and helping communities change the current culture of research.
She has led research identifying intrinsic equity issues in the cardiovascular research community in Australia (https://pubmed.ncbi.nlm.nih.gov/32839116/), followed by research to find solutions for these issues (https://pubmed.ncbi.nlm.nih.gov/35577952/), resulting in the 2021 Women’s Agenda Emerging Leader in STEM award.
Outside work, Francine enjoys baking, travelling, spending time with family, friends and her dogs, and reading books.
https://orcid.org/0000-0003-4920-9991
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Novel immunotherapies in lymphoma
Dr Sean Harrop is a dual-trained haematologist having completed his clinical and laboratory haematology training at the Peter MacCallum Cancer Centre, Royal Melbourne Hospital and St Vincent’s Hospital Melbourne. He is the current clinical haematology fellow (aggressive lymphoma) at Peter MacCallum and a PhD student in the Cancer Immunology Program in the Neeson Lab.
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Environmental exposure to function of lung epithelial stem cell biology
Dr Clare Weeden has recently commenced as a Laboratory Head at WEHI in 2025, supported by the CSL Centenary Fellowship.
Dr Weeden specialises in lung epithelial cell biology in the context of homeostasis, inflammation, and lung cancer, particularly in people who don’t smoke. Her work endeavours to understand how past environmental exposures shape the responses of lung cells and the molecular mechanisms underlying this cellular recall, with the aim to develop novel early detection strategies for lung disease.
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DNA repair on the Fanconi anaemia pathway
Associate Professor Wayne Crismani is an internationally recognised expert in DNA repair, with a particular focus on Fanconi anaemia (FA)—a cancer-predisposition and bone marrow failure syndrome marked by extreme sensitivity to DNA damage. Based at St Vincent’s Institute in Melbourne, he leads a research program dedicated to understanding the genetic, cellular, and reproductive consequences of FA. He is currently supported by a Victorian Cancer Agency Mid-Career Fellowship and funding from the National Health and Medical Research Council.
