South Australian Health and Medical Research Institute, also known as SAHMRI has had significant impacts in various areas over the past ten years, and this year is celebrating its 10 year anniversary with a week of events.
Ahead of the anniversary, Executive Director, Professor Maria Makrides spoke to Bench Side Story about 3 achievements in the past 10 years that have had significant impact
- International leadership breakthroughs in leukaemia research
- Culturally appropriate Indigenous health research and clinical care
- Omega 3 fatty acids as a preterm birth prevention
Looking ahead, SAHMRI is not standing still, and the newly built, and when fully installed, Australian Bragg Centre for Proton Therapy and Research will be Australia’s first proton therapy centre and the first of its kind in the Southern Hemisphere.
The Centre will occupy the ground floor and three below-ground levels of the Australian Bragg Centre building which has recently been completed on the eastern side of the distinctive SAHMRI building on North Terrace, Adelaide.
The centre will also be an integral part in a global network undertaking proton therapy research.
Proton therapy is a precise, non-invasive radiotherapy that can destroy cancer cells while minimising damage to surrounding healthy tissue including vital organs.
As a relatively new treatment option and one that remains expensive and not widely available, proton therapy has only been validated against a small range of cancers. The technology is potentially beneficial in treating many other diseases, but more research is needed in these areas to prove its efficacy.
SAHMRI represents an exciting and unique statewide concept, bringing together basic and translational research, South Australia’s three universities and the health system. SAHMRI works in collaboration with its partners to provide a clear focal point for health and medical research, including paving the way for new partnerships, innovative research projects and improved health outcomes.
The career opportunities at SAHMRI for researchers ranges from early career stage to recognised experts in their fields. Nothing unique with that, but the ability to validate discovery makes SAHRMI a unique work environment.
According to Executive Director, Professor Maria Makrides, “The culture is characterised by being fast, focused, friendly, flexible, and fun, which has fostered innovation, collaboration, and the ability to take risks and learn from both successes and failures to make advancements quickly.”
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Radiation therapy techniques and combination treatments for sarcoma
Professor Angela Hong MBBS, MMed, PhD, FRANZCR is a Professor at Sydney Medical School of the University of Sydney. She is a radiation oncologist and has been a member of the Multidisciplinary Bone and Soft Tissue Tumour Clinic at Royal Prince Alfred Hospital/Chris O’Brien Lifehouse for the past 15 years.
As a radiation oncologist located in Sydney, Australia, Professor Hong is focused on treating patients with bone and soft tissue sarcoma. And as a clinician scientist, her research focuses on developing innovative radiation therapy technique and combination treatments to improve the outcome for patients with sarcoma.
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Biostatistics in Clinical Trials
As a biostatistician working in research and clinical settings, Kate Francis plays a vital role in ensuring all projects adhere to best practice guidelines and are transparently reported. She has served as the lead statistician for the analysis of clinical trials across a broad range of subject areas, including neonatal resuscitation, BCG for allergy and infection, convulsive status epilepticus and her work has been published in the top journals such as The New England Journal of Medicine, JAMA, and The Lancet. Most recently she was awarded the 2025 Excellence in Trial Statistics Award for her work on the PLUSS trial.
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Elite athlete physical and mental health impact performance
Understanding the interaction between genes and lifestyle factors in response to stress can lead to potential therapeutic interventions for stress-related disorders. This research is crucial for promoting health and well-being.
Professor Mehta has recently commenced research into elite athlete physical and mental health impact performance, with research at the intersection of statistics, genomics, and mental health. This research is ahead of, and in anticipation of, the Summer Olympics in Brisbane in 2032.
