RESEARCHER PROFILE
Dr Josephine Wright
South Australian Health and Medical Research Institute (SAHMRI)
Filmed September 2023
Dr Josephine Wright is a Senior Research Fellow in the Gut Cancer group. She has been developing a translational network of labs, hospitals and clinics to enable validation of new approaches to prevent and treat colorectal and gastric cancer. Her key focus is studying human tumour organoids to better personalise therapy in cancer.
Dr Wright is part of an international team of researchers from Adelaide and the United States that has engineered bacteria capable of detecting mutated DNA released from colorectal cancer cells, opening the door to faster disease detection.
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CASE STUDY: Transforming surgical waitlist into a ‘preparation list’
The DIAMONDS initiative aims to transform the surgical waitlist into a “preparation list,” enabling healthcare professionals to optimise patient care in the months leading up to elective surgery starting at pre-admission phase.
Patients are will be able to complete pre-admission forms online, receive timely updates, and access educational resources to ensure thorough preparation. This will allow staff to spend more time with patients.
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Systems genetics to determine risk of developing diabetes complications
Professor Morahan invented the term “Systems Genetics” for the science field that examines how genetic variants can affect whole networks of genes and whole systems; there are now several laboratories and institutes of systems genetics around the world. He also developed the next-generation genetic resource, The Gene Mine, the most powerful of its type in the world, used globally in rapid mapping and identification of genes. Collaborators nationally and internationally have tested The Gene Mine for traits and diseases in which they specialise.
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Liver cancer & patient-derived tumour organoids
Dr Benjamin Dwyer is a translational cancer researcher driven by a clear purpose: to ensure discoveries made in the laboratory genuinely improve outcomes for patients.
Based at Curtin University, he established and now leads the organoid platform within the Liver Cancer Collaborative and directs the WA Organoid Innovation Hub, working at the intersection of biology, medicine and biotechnology to accelerate new treatments for liver cancer.
