RESEARCHER PROFILE
Professor Sant-Rayn Pasricha (Filmed April 2024)
Study lead and Acting WEHI Deputy Director
WEHI (Walter and Eliza Hall Institute of Medical Research)
Clinical Haematologist Royal Melbourne Hospital & Peter MacCallum Cancer Centre
Professor Sant-Rayn Pasricha is the Acting Deputy Director at the Walter Eliza Hall Institute of Medical Research in Melbourne, Australia. He is also a clinical haematologist at the Royal Melbourne Hospital and the Peter MacCallum Cancer Centre. From a young age, Prof Pasricha dreamed of becoming a doctor and found joy in learning about the human body and how to care for patients. After completing medical school, he developed a passion for working in low and middle-income countries, which led him to spend time working in East Timor, India, and Central Australia with First Nations communities.
Prof Pasricha went on to specialise in haematology, which covers a wide range of fields, including cancer biology, immunology, transplant, nutrition, pathology, and red cell blood transfusion. He completed his haematology training and earned a PhD in global health, which allowed him to explore his interests in public health, global health, and haematology. Prof Pasricha focused his research on the significant and common issue of anaemia, particularly in low-income countries. He conducted field studies in the villages of Karnataka, India, and spent five years working in the lab at the University of Oxford to understand iron biology.
Currently, Pasricha runs his own lab at WEHI, where he serves as a lab and division head, conducting anaemia research. His lab covers a range of basic science research areas, including exploratory biology on how red blood cells are made, iron biology, and the role of inflammation in anaemia. Additionally, his lab conducts global trials in Africa and South Asia to prevent and treat anaemia and nutritional disorders in children and pregnant women.
Prof Pasricha’s lab completed a large analysis on haemoglobin thresholds to define anaemia, which informed the new World Health Organization guidelines on anaemia. The lab also conducts large randomised controlled field studies on ways to treat anaemia in pregnancy and young babies in Malawi and Bangladesh.
Prof Pasricha is passionate about improving the health of people in low-income countries and finding innovative solutions to improve the health of mothers and children in particular. He focuses on anaemia, nutrition, and exposure to infectious diseases. Prof Pasricha is also deeply curious about how the body works and how different systems interact with each other and the outside environment.
As a clinician scientist, Pasricha finds his job both busy and fulfilling. He enjoys taking care of patients, keeping up with breakthroughs in medicine, and running a research program. Prof Pasricha spends a substantial amount of time thinking about his work and planning the next experiment or study. Outside of work, he enjoys spending time with his three children and being involved in the community.
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Impact of Leukaemia Foundation’s Research Funding into Blood Cancer
Bill Stavreski is the Head of Research at the Leukaemia Foundation who talks about the research impact in recent years. The Foundation itself marks its 25th anniversary in 2025, having funded a wide range of health and medical research since 2000. With a focus on basic science, health services research, treatment, and care, the organisation has invested nearly $90 million (adjusted in current dollars terms) in approximately 370 research grants over the years.
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Therapies for chronic myeloid leukaemia
Professor Tim Hughes is an international expert in the biology and treatment of leukaemia. He led the establishment of the molecular response criteria that are used world-wide to measure response in chronic myeloid leukaemia (CML) and has led many of the key Global and National trials. His group has successfully developed predictive bioassays and molecular targets that influence the way CML patients are managed world-wide. He has published over 350 papers that have been cited over 65,000 times.
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Blister management and impact on firefighters
David Burns, a Senior Paramedic with LifeAid, a private paramedicine company in Victoria and, has a diverse background in healthcare. He began his career as a registered nurse, progressing to critical care nursing specialising in liver transplants and cardiovascular surgery.
At the Australasian College of Paramedicine International Conference, David presented research focused on the foot care of firefighters during prolonged bushfire campaigns. During the 2019-2020 bushfires, over 10,000 firefighters sought care, with nearly 50% requiring attention for foot-related issues. David emphasised that inadequate foot care could bench firefighters for up to 10 days, diminishing their ability to protect communities and critical infrastructure. Recognising the economic benefits of prioritising firefighter health, David advocates that ensuring their well-being allows communities to recover effectively and enhances safety for all involved in firefighting efforts.
