RESEARCHER PROFILE
Professor Sant-Rayn Pasricha (Filmed April 2024)
Study lead and Acting WEHI Deputy Director
WEHI (Walter and Eliza Hall Institute of Medical Research)
Clinical Haematologist Royal Melbourne Hospital & Peter MacCallum Cancer Centre
Professor Sant-Rayn Pasricha is the Acting Deputy Director at the Walter Eliza Hall Institute of Medical Research in Melbourne, Australia. He is also a clinical haematologist at the Royal Melbourne Hospital and the Peter MacCallum Cancer Centre. From a young age, Prof Pasricha dreamed of becoming a doctor and found joy in learning about the human body and how to care for patients. After completing medical school, he developed a passion for working in low and middle-income countries, which led him to spend time working in East Timor, India, and Central Australia with First Nations communities.
Prof Pasricha went on to specialise in haematology, which covers a wide range of fields, including cancer biology, immunology, transplant, nutrition, pathology, and red cell blood transfusion. He completed his haematology training and earned a PhD in global health, which allowed him to explore his interests in public health, global health, and haematology. Prof Pasricha focused his research on the significant and common issue of anaemia, particularly in low-income countries. He conducted field studies in the villages of Karnataka, India, and spent five years working in the lab at the University of Oxford to understand iron biology.
Currently, Pasricha runs his own lab at WEHI, where he serves as a lab and division head, conducting anaemia research. His lab covers a range of basic science research areas, including exploratory biology on how red blood cells are made, iron biology, and the role of inflammation in anaemia. Additionally, his lab conducts global trials in Africa and South Asia to prevent and treat anaemia and nutritional disorders in children and pregnant women.
Prof Pasricha’s lab completed a large analysis on haemoglobin thresholds to define anaemia, which informed the new World Health Organization guidelines on anaemia. The lab also conducts large randomised controlled field studies on ways to treat anaemia in pregnancy and young babies in Malawi and Bangladesh.
Prof Pasricha is passionate about improving the health of people in low-income countries and finding innovative solutions to improve the health of mothers and children in particular. He focuses on anaemia, nutrition, and exposure to infectious diseases. Prof Pasricha is also deeply curious about how the body works and how different systems interact with each other and the outside environment.
As a clinician scientist, Pasricha finds his job both busy and fulfilling. He enjoys taking care of patients, keeping up with breakthroughs in medicine, and running a research program. Prof Pasricha spends a substantial amount of time thinking about his work and planning the next experiment or study. Outside of work, he enjoys spending time with his three children and being involved in the community.
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Genetics of the choroid and impact on eye health
Dr Samantha Lee is a Senior Research Fellow at Lions Eye Institute and the University of Western Australia. Dr Lee obtained her PhD in 2017 and the Queensland University of Technology and has since been working on the genetics and environmental causes of various eye diseases, with a focus on glaucoma and myopia. She has published 57 full-length scientific papers and her work has been cited over 1,000 times. She serves on the Editorial Board for the journal BMC Ophthalmology and Scientific Reports, and on the Research Advisory Committee for the Ophthalmic Research Institute of Australia.
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Genetic alterations in prostate cancer initiation and progression
Watch Dr Kelsie Raspin, a dedicated Postdoctoral Research Fellow specialising in Cancer Genetics at Menzies Institute for Medical Research, University of Tasmania, talk on bridging a critical knowledge gap in the understanding of genetic alterations implicated in prostate cancer initiation and its progression into metastatic forms.
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Interventions for improving outcomes of children who are deaf or hard of hearing
Professor Teresa Ching is a Conjoint Professor at NextSense Institute and Macquarie University, and an Honorary Professor at the University of Queensland in Australia. Her current research focuses on devising culturally sensitive practices in early detection and intervention to maximise children’s outcomes. Working with international colleagues, her current research is also directed towards developing global guidelines and recommendations for hearing screening beyond the newborn period, so that all children can benefit from early detection and intervention. The ultimate goal is to attain equity of care and outcomes for all children with hearing difficulties.
