RESEARCH CASE STUDY Role of Exercise in Metabolic Associated Fatty Liver Disease (Filmed 2024)
Dr. Shelley Keating AES AEP* is an Accredited Exercise Physiologist, a researcher, and a senior lecturer at the School of Human Movement and Nutrition Sciences at the University of Queensland in Brisbane, Australia. Dr. Keating’s research primarily focuses on the role of exercise in the management of metabolic dysfunction associated steatotic liver disease (MASLD), previously known as non-alcoholic fatty liver disease. MASLD affects a significant portion of the global adult population, with many individuals unaware of their condition.
The condition is strongly linked with the development of Type 2 diabetes, heart disease, and various liver-related consequences. Dr. Keating’s research emphasises lifestyle interventions, particularly the role of exercise, in managing MASLD. Her work has shown that aerobic exercise, independent of weight loss, plays a crucial role in reducing liver fat and improving liver health.
Through clinical trials, Dr. Keating and her team have explored the impact of different doses of supervised aerobic exercise on individuals with obesity and MASLD. Their findings suggest that aerobic exercise, at various durations and intensities, yields benefits for reducing liver fat. They recommend 150 to 240 minutes of moderate to vigorous intensity aerobic exercise per week as beneficial for improving liver health. Moreover, even lower doses of exercise, such as 135 minutes per week, have shown positive effects.
Dr. Keating has collaborated with Exercise and Sports Science Australia and international experts in creating exercise guidelines for the management of MASLD, which have been adopted in numerous policies and guidelines worldwide. Currently, her focus is on designing tailored exercise solutions to help individuals living with MASLD sustain long-term exercise behaviours based on their needs, perspectives, and experiences.
* AES is the acronym for Accredited Exercise Scientist (AES), AEP is the acronym for Accredited Exercise Physiologist
-
Food and fasting periods as medicine to prevent disease
Professor Leonie Heilbronn is based at the South Australian Health and Medical Research Institute (SAHMRI), where she leads the Obesity and Metabolism laboratory. Her research is at the interface between basic and clinical science. She is internationally recognised for her work in nutritional modulation in humans and has made major contributions to our current understanding of mechanisms underlying conditions such as insulin resistance, particularly inflammation and lipid metabolism. She has also contributed significantly to current concepts of caloric restriction (CR), intermittent fasting (IF) and time restricted eating (TRE) in humans. She has published more than 110 peer reviewed papers in scientific journals and is an Associate Editor of Obesity, and Obesity Research and Clinical Practice.
-
Inner ear organoids for the study of human hearing and balance
Dr Jackie Ogier is an auditory neuroscientist, with a research focus on the molecular biology of hair cells, the specialised sensory receptors in the ear that detect sound and balance. She is a postdoctoral research fellow in the laboratory of A/Prof Bryony Nayagam, supported by a prestigious Passe and Williams foundation fellowship.
Dr Ogier’s experience broadly spans the genetics of hearing loss, disease modelling, micro dissection, primary cell culture, stem cell culture, organoids, and proteomics. Overall, she aims to generate knowledge of hearing and vestibular sensory biology.
-
Podiatric Research In Children, the workforce and the LGBTQIA+ community
Professor Williams holds the role of Deputy Head of School, School of Primary and Allied Health Care, and course coordinator of the Doctor of Podiatric Medicine degree. She is a podiatrist, and has held professional roles in community health, acute and subacute services in child health care teams, research leadership and professional governance.
