HORMONE RECEPTOR POSITIVE BREAST CANCER AND THERAPY RESISTANCE
Professor Elgene Lim
Laboratory Head Connie Johnson Breast Cancer Research Lab,
Garvan Institute of Medical Research, Sydney &
Oncologist, The Kinghorn Cancer Centre, St Vincent’s Hospital, Sydney
RESEARCHER PROFILE (Filmed in Brisbane, Queensland, Australia | October 2024)
Prof Elgene Lim is a medical oncologist at St Vincent’s Hospital and Head of the Connie Johnson Breast Cancer Research Lab at the Garvan Institute. Following his PhD at the Walter & Eliza Hall Institute where he identified the aberrant cells in carriers of the BRCA1 mutant gene, a hereditary breast cancer syndrome as the culprit cells giving rise to breast cancer, he furthered his research and clinical training at the Dana-Farber Cancer Institute and Harvard Medical School. He was awarded the National Breast Cancer Foundation Practitioner Fellowship in 2014 and returned from Boston to Australia. In 2017, he was awarded the inaugural National Breast Cancer Foundation Endowed Chair, and subsequently appointed the Principal Cancer Theme Lead at UNSW.
His research focus is in the area of breast cancer, specifically bringing laboratory findings into clinical studies and evaluation of novel therapies in clinical trials. His team, in partnership with patients, have established a large panel of patient derived breast cancer avatars in mice, which allow for the study of breast cancer biology and the evaluation of novel therapies.
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Stem cell therapies for enteric neuropathies
Dr Stamp is a Group Leader in the Department of Anatomy and Physiology at the University of Melbourne, Australia. Dr Stamp’s PhD research (with Prof Martin Pera, Monash University) focused on the derivation of hepatopancreatic progenitors from human embryonic stem cells. He then joined the lab of Dr Don Newgreen at the Murdoch Childrens Research Institute where he began working on development of the enteric nervous system (ENS), before joining Prof Heather Young’s lab at the University of Melbourne, where he focused on developing a stem cell therapy to treat gut motility disorders such as the paediatric enteric neuropathy Hirschprung disease.
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Outcomes of Corneal Allergenic Intrastromal Ring Segment (CAIRS) Surgery
Dr David Gunn is an ophthalmologist specialising in cornea, cataract, and refractive surgery at the Queensland Eye Institute and Focus Vision in Brisbane, Queensland. His journey into ophthalmology began during medical school, inspired by a mentor. His current research examines outcomes for patients undergoing Corneal Allergenic Intrastromal Ring Segment (CAIRS) surgery.
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Digital Biomarkers and AI for Optimal Diagnosis, Treatment, and Decision-Making
Associate Professor Johan Verjans is a clinician-scientist with a strong focus on cross-disciplinary translational research. In his role as Deputy Director at the Australian Institute for Machine Learning (AIML)—one of the world’s premier machine learning institutes, with over 200 researchers—and as Group Leader of Artificial Intelligence at the South Australian Health and Medical Research Institute (SAHMRI), he integrates his expertise in molecular medicine, clinical research, and advanced imaging with machine learning applications. This unique combination enables him to drive the translation of cutting-edge AI research into practical medical applications. He works with global teams from multinationals on AI problems.
