INFECTIONS AND OTHER LUNG DISEASES USING MODELS OF HUMAN LUNG TISSUE GROWN FROM STEM CELLS
Dr Rhiannon Werder,
Team Leader
Murdoch Children’s Research Institute
Melbourne, Victoria, Australia
RESEARCHER PROFILE
Filmed in Melbourne, Australia | February 2025
Released on the United Nations International Day of Women and Girls in Science, 11th February 2025 @WomenScienceDay
Dr Rhiannon Werder is a Team Leader at Murdoch Children’s Research Institute leading a multidisciplinary team, combining expertise in stem cell biology and immunology, to develop new therapies for lung diseases. Her research centres around induced pluripotent stem cells to investigate respiratory diseases, spanning acute respiratory infections to chronic lung diseases. Using stem cells, Dr Werder’s team creates models of human lung tissue. With these models, Dr Werder is investigating how human-specific pathogens infect different regions of the lung, the ensuing immune responses, and how the lung repairs itself after infections, especially in people with preexisting lung diseases.
After completing her PhD in Mucosal Immunology at the University of Queensland, Dr Werder was awarded a NHMRC CJ Martin Fellowship to undertake postdoctoral training at the Center for Regenerative Medicine at Boston University. At the height of the COVID-19 pandemic, Dr Werder’s research led to significant findings, including the first discovery of how the lung epithelium responds to the SARS-CoV-2 virus. She has also pioneered new gene-editing techniques in iPSC-derived epithelial cells to understand chronic lung disease inception. The impact of her research has been recognised by prestigious awards including the Metcalf Prize for Stem Cell Research by National Stem Cell Foundation of Australia.
https://orcid.org/0000-0002-6432-4587
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Nanoparticles & microparticles to combat antimicrobial resistance
Dr Anjana Jayasree is an emerging research leader in biomaterials, tissue engineering and nanotechnology, recognised internationally for her innovative work on antimicrobial nanoparticles and regenerative therapies. A Postdoctoral Research Fellow at The University of Queensland, she operates at the intersection of materials science, drug delivery and cellular biology, developing advanced metallic-based nanotechnologies to improve both human and animal health outcomes. Her expertise spans nanoparticle synthesis, cell–material interactions, and the design of sophisticated in vitro models to investigate soft-tissue integration, osseointegration, angiogenesis and biofilm formation.
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Mental health research on first responders in regional, rural and remote Australia
Dr Rikki Jones has been awarded to date a total of over $430,000 in research funding. She is currently leading four large national research teams focusing on rural health and sustainable rural health workforce (include mental health of first responders, sexual violence in rural Australia, virtual simulated nursing placements, and nursing students experience with online learning, connection and transitioning to practice).
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Next generation nanomedicine and radiopharmaceuticals to treat cancer
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Professor Thurecht’s work focuses on nanomedicine and spans across the Australian Institute for Bioengineering and Nanotechnology and the Centre for Advanced Imaging, at the University of Queensland in Australia.
