RESPIRATORY HEALTH AND THE MICROBIOME IN THE LUNG ENVIRONMENT
Dr Steven Taylor, Postdoctoral Researcher,
Head of Respiratory Health Group
South Australian Health and Medical Research Institute (SAHMRI)
Adelaide, South Australia
RESEARCHER PROFILE
Filmed in Adelaide, South Australian | December 2024
Dr Taylor leads the Respiratory Health Group within the Microbiome and Host Health Program. His research employs tailored techniques that allow the lung environment to be characterised to a high level of accuracy, including detailed measurements of airway microbiology (microbiome), mucus composition, and inflammation. This information is used to identify predictive markers of chronic lung disease severity as well as determine effective forms of therapy.
Dr Taylor is one of the researchers leading The GRACE study, a project that aims to investigate the carriage and transfer of resistant bacteria or ‘superbugs’ in residential aged care.
Funded by the National Health & Medical Research Council’s Medical Research Future Fund, this study will produce new evidence to help us to improve facility management, including cleaning and hygiene practices, to prevent the spread of harmful bacteria, and ultimately improve the health of aged care residents and the wider community.
Dr Taylor also recently led a study that showed genetics may play a crucial part in the efficacy of probiotics. Published in ISME Journal in June the study, focussed on the interactions between probiotics and individual genetic traits. Researchers say their findings suggest a more tailored approach to using probiotics may have the potential to significantly enhance gut microbiome regeneration and related health benefits.
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Professor Matthew Kiernan
BRAIN AND MIND CENTRE
@ UNIVERSITY OF SYDNEY, NEW SOUTH WALES AUSTRALIA -
World-first clinical trial improves patient outcomes for kidney transplants (2023)
A world-first clinical trial conducted at the Royal Adelaide Hospital (RAH) and at hospitals across Australia and New Zealand has identified the best fluid treatment to reduce the risk of patients requiring dialysis after a kidney transplant.
Around one in three people who receive a kidney transplant suffer delayed graft function, which means the transplant doesn’t work immediately and they require dialysis.
The lead-author of the study, was Royal Adelaide Hospital Nephrologist and University of Adelaide researcher, Dr Michael Collins.
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CASE STUDY Link between levels of extracellular vesicles in the blood and tissue damage caused by diseases
A landmark study led by WEHI and La Trobe University has found a potential new diagnostic marker that could be used to better detect the level of tissue damage in our bodies.
This study revealed, for the first time, a link between levels of EVs in the blood and tissue damage caused by diseases such as leukaemia.
Researchers hope to leverage the critical new insight to develop a blood test to monitor cancer patients with tissue damage, which could, in future, enhance treatment strategies for blood cancers and other diseases.
