RESPIRATORY HEALTH AND THE MICROBIOME IN THE LUNG ENVIRONMENT
Dr Steven Taylor, Postdoctoral Researcher,
Head of Respiratory Health Group
South Australian Health and Medical Research Institute (SAHMRI)
Adelaide, South Australia
RESEARCHER PROFILE
Filmed in Adelaide, South Australian | December 2024
Dr Taylor leads the Respiratory Health Group within the Microbiome and Host Health Program. His research employs tailored techniques that allow the lung environment to be characterised to a high level of accuracy, including detailed measurements of airway microbiology (microbiome), mucus composition, and inflammation. This information is used to identify predictive markers of chronic lung disease severity as well as determine effective forms of therapy.
Dr Taylor is one of the researchers leading The GRACE study, a project that aims to investigate the carriage and transfer of resistant bacteria or ‘superbugs’ in residential aged care.
Funded by the National Health & Medical Research Council’s Medical Research Future Fund, this study will produce new evidence to help us to improve facility management, including cleaning and hygiene practices, to prevent the spread of harmful bacteria, and ultimately improve the health of aged care residents and the wider community.
Dr Taylor also recently led a study that showed genetics may play a crucial part in the efficacy of probiotics. Published in ISME Journal in June the study, focussed on the interactions between probiotics and individual genetic traits. Researchers say their findings suggest a more tailored approach to using probiotics may have the potential to significantly enhance gut microbiome regeneration and related health benefits.
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Developing upper limb motor biomarkers of dementia
Kaylee is currently a research fellow with the Wicking Dementia Research and Education Centre at the University of Tasmania. She has recently submitted her PhD thesis, reporting the findings of her research on developing upper limb motor biomarkers of dementia. She has postgrad degrees in physiotherapy and experience working in the community and aged care across Tasmania for several years, where she worked with people with dementia.
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Identification & characterisation of molecular drivers of therapeutic resistance
Professor Pieter Eichhorn is an internationally experienced cancer biologist and research leader whose career has been defined by high-impact contributions at the interface of functional genomics, translational oncology, and research infrastructure strategy.
He completed his PhD at the University of Newcastle upon Tyne, contributing to the cloning of the gene associated with Cornelia de Lange Syndrome, before undertaking postdoctoral training at the Netherlands Cancer Institute in the laboratory of René Bernards. There, he performed pioneering functional genetic screens that identified key regulators of oncogenesis and therapy resistance, including critical roles for the PI3K signalling pathway in resistance to targeted breast cancer therapies.
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Touched by bowel cancer and chasing science outcomes
Dr Josephine Wright is a Senior Research Fellow in the Gut Cancer group. She has been developing a translational network of labs, hospitals and clinics to enable validation of new approaches to prevent and treat colorectal and gastric cancer. Her key focus is studying human tumour organoids to better personalise therapy in cancer.
