RESPIRATORY HEALTH AND THE MICROBIOME IN THE LUNG ENVIRONMENT
Dr Steven Taylor, Postdoctoral Researcher,
Head of Respiratory Health Group
South Australian Health and Medical Research Institute (SAHMRI)
Adelaide, South Australia
RESEARCHER PROFILE
Filmed in Adelaide, South Australian | December 2024
Dr Taylor leads the Respiratory Health Group within the Microbiome and Host Health Program. His research employs tailored techniques that allow the lung environment to be characterised to a high level of accuracy, including detailed measurements of airway microbiology (microbiome), mucus composition, and inflammation. This information is used to identify predictive markers of chronic lung disease severity as well as determine effective forms of therapy.
Dr Taylor is one of the researchers leading The GRACE study, a project that aims to investigate the carriage and transfer of resistant bacteria or ‘superbugs’ in residential aged care.
Funded by the National Health & Medical Research Council’s Medical Research Future Fund, this study will produce new evidence to help us to improve facility management, including cleaning and hygiene practices, to prevent the spread of harmful bacteria, and ultimately improve the health of aged care residents and the wider community.
Dr Taylor also recently led a study that showed genetics may play a crucial part in the efficacy of probiotics. Published in ISME Journal in June the study, focussed on the interactions between probiotics and individual genetic traits. Researchers say their findings suggest a more tailored approach to using probiotics may have the potential to significantly enhance gut microbiome regeneration and related health benefits.
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Genetic disease research imitating function and architecture of organs
Professor Wolvetang was among the first to bring the first human embryonic stem cells to Queensland, with his Wolvetang Group at the AIBN now renowned for its work with organoids: growing them, studying them, and using them to try and understand diseases and human development.
Using cutting edge technology, Professor Wolvetang designs and grows organoids both for their own work and for labs across the country, coaxing pluripotent stem cells or tissue samples into 3D structures that mimic the function and architecture of real brains, livers, kidneys, spinal cords, and intestines.
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Genetic alterations in prostate cancer initiation and progression
Watch Dr Kelsie Raspin, a dedicated Postdoctoral Research Fellow specialising in Cancer Genetics at Menzies Institute for Medical Research, University of Tasmania, talk on bridging a critical knowledge gap in the understanding of genetic alterations implicated in prostate cancer initiation and its progression into metastatic forms.
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CASE STUDY: Transforming surgical waitlist into a ‘preparation list’
The DIAMONDS initiative aims to transform the surgical waitlist into a “preparation list,” enabling healthcare professionals to optimise patient care in the months leading up to elective surgery starting at pre-admission phase.
Patients are will be able to complete pre-admission forms online, receive timely updates, and access educational resources to ensure thorough preparation. This will allow staff to spend more time with patients.
