THERAPIES FOR CHRONIC MYELOID LEUKAEMIA
Professor Tim Hughes
Clinical Director Precision Cancer Medicine Theme, South Australian Health and Medical Research Institute (SAHMRI)
& Consultant Haematologist, Royal Adelaide Hospital, South Australia
RESEARCHER PROFILE (Filmed in Adelaide, South Australia | December 2024)
Professor Tim Hughes is the Chronic Myeloid Leukaemia Group Leader at SAHMRI, Clinical Director in the Precision Cancer Medicine Theme at SAHMRI and Consultant Haematologist in the Division of Haematology at SA Pathology and at the Royal Adelaide Hospital.
He is also Inaugural Fellow of the Australian Academy of Health and Medical Sciences (AAHMS) and Fellow of the Australian Academy of Science.
Professor Hughes is an international expert in the biology and treatment of leukaemia. He led the establishment of the molecular response criteria that are used world-wide to measure response in chronic myeloid leukaemia (CML) and has led many of the key Global and National trials. His group has successfully developed predictive bioassays and molecular targets that influence the way CML patients are managed world-wide. He has published over 350 papers that have been cited over 65,000 times.
He has been recognised for his achievements with several national awards including the GSK Award for Research Excellence in 2017 for pioneering the use of tyrosine kinase inhibitors (TKIs) and the Ramaciotti Medal for Excellence in Biomedical Research in 2019. He was also awarded the International CML Foundation Goldman Prize in 2017 for lifetime contributions to improving outcomes for patients with CML.
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Peripheral intravenous catheter management
Dr Grace Xu is a clinician-researcher, senior nurse practitioner, and emerging implementation scientist with more than 16 years of emergency nursing experience. She is a Fellow of the College of Emergency Nurses Australasia and a Centaur Fellow. She also leads the Early Career Researcher/Clinician Researcher portfolio within the Alliance for Vascular Access Teaching and Research group.
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Muscle Cell Communication and Repair
Dr. William Roman is a Group Leader at the Australian Regenerative Medicine Institute (ARMI) at Monash University. He obtained his PhD from Paris Descartes University and Freie University of Berlin, focusing on nuclear positioning during skeletal muscle development. Dr. Roman’s research journey has taken him across the globe, including postdoctoral work in Barcelona, tissue engineering in Lisbon, and a brief stint at Stanford University.
At ARMI, Dr. Roman leads innovative research on intercellular communication within muscle organs. His work involves growing human muscles on chips to understand how skeletal muscle cells interact with neurons and tendons. This research aims to develop better models for studying muscle diseases, drug screening, and even applications in cellular agriculture and biorobotics.
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Supportive care for people living with or beyond cancer treatment
Dr Hannah Wardill is a Hospital Research Foundation Fellow and lead of the Supportive Oncology Research Group (SORG), in the School of Biomedicine, University of Adelaide and Precision Cancer Medicine Theme, South Australian Health and Medical Research Institute (SAHMRI). She is an Executive Board Member of the Multinational Association for Supportive Care in Cancer / International Society for Oral Oncology (MASCC/ISOO) and Chair of both MASCC/ISOO Patient Partnership Committee & the Palliative Care Clinical Studies Collaborative (PaCCSC) Cancer Symptom Trials (Gut Dysfunction Node; supported by Cancer Australia).
