OCULAR DISEASE AND EARLY ONSET MYOPIA
Dr Jessica Mountford
Brian King Fellow &
Head of Functional Molecular Vision Group
Lions Eye Institute, Western Australia
RESEARCHER PROFILE
Filmed in Perth, Western Australia | November 2024
Dr Jessica Mountford received her highly ranked PhD from Monash University, Melbourne, in 2012, in the field of biochemistry and clinical haematology. Her work investigating novel ways to prevent thrombosis, a leading cause of heart attack and stroke, led to a first author publication in Nature Communications.
Following this, Dr Mountford relocated to Perth and went on to complete two post-doctoral appointments at the University of Western Australia, where she began research on the comparative evolution of visual and non-visual opsin across species of vertebrate, from the primitive lamprey to human.
During this period Dr Mountford began researching novel genetic variants associated with myopia development. With Adjunct Research Fellow appointments held at La Trobe University in Melbourne, and the University of Western Australia, Dr Mountford is currently the 6th Brian King Fellow and the Head of the Functional Molecular Vision Group at the Lions Eye Institute in Perth where she researches both the genetic and environmental factors involved in the development of early-onset myopia.
Dr Mountford has successfully established Western Australia’s first and only ocular genetic screening platform using zebrafish and utilises this model to help elucidate some of the complex gene-environment interactions responsible for the development of myopia.
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Environmental exposure to function of lung epithelial stem cell biology
Dr Clare Weeden has recently commenced as a Laboratory Head at WEHI in 2025, supported by the CSL Centenary Fellowship.
Dr Weeden specialises in lung epithelial cell biology in the context of homeostasis, inflammation, and lung cancer, particularly in people who don’t smoke. Her work endeavours to understand how past environmental exposures shape the responses of lung cells and the molecular mechanisms underlying this cellular recall, with the aim to develop novel early detection strategies for lung disease.
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Muscle Cell Communication and Repair
Dr. William Roman is a Group Leader at the Australian Regenerative Medicine Institute (ARMI) at Monash University. He obtained his PhD from Paris Descartes University and Freie University of Berlin, focusing on nuclear positioning during skeletal muscle development. Dr. Roman’s research journey has taken him across the globe, including postdoctoral work in Barcelona, tissue engineering in Lisbon, and a brief stint at Stanford University.
At ARMI, Dr. Roman leads innovative research on intercellular communication within muscle organs. His work involves growing human muscles on chips to understand how skeletal muscle cells interact with neurons and tendons. This research aims to develop better models for studying muscle diseases, drug screening, and even applications in cellular agriculture and biorobotics.
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Dr Ryan O’Hare Doig
NEIL SACHSE CENTRE FOR SPINAL CORD RESEARCH (SAHMRI)
SOUTH AUSTRALIA
AUSTRALIA
