DENTAL CARE IMPROVEMENTS USING INFORMATICS AND ARTIFICIAL INTELLIGENCE
Professor Heiko Spallek
Head of School and Dean of The University of Sydney School of Dentistry &
Member of Scientific Advisory Committee, Dentroid
RESEARCHER PROFILE
Filmed in Sydney, Australia | December 2024
Professor Heiko Spallek is the Head of School and Dean of the Sydney Dental School, as well as a member of the Scientific Advisory Committee for Dentroid, a startup in Australia aiming to revolutionise dentistry with laser technology. He has gained extensive experience in various roles at research-intensive institutions across three different continents.
Professor Spallek advanced his dental knowledge by studying computer information science in the US, particularly in Philadelphia. He conducted research for 20 years in the US at the intersection of dentistry and informatics.
As the Dean of Dentistry, he remains involved with a group in the US focused on improving dental care through informatics and artificial intelligence. In Australia, he finds the opportunity to work with Dentroid particularly engaging, as the startup seeks to enhance dental care by eliminating needles and drills to reduce patient discomfort.
Professor Spallek notes that there haven’t been significant changes in dentistry over the past few decades, aside from incremental improvements. He finds it both challenging and interesting to address the stagnation in the field, despite the availability of better materials in dentistry.
He points out that traditional dental treatments still heavily rely on local anaesthesia administered through long needles, as well as high-pitched noises and vibrations from hand pieces, which create discomfort for patients. Furthermore, dentists often have to hunch over patients’ mouths, exposing themselves to infectious spray.
Dentroid is attempting to create a paradigm shift by starting treatments with a light-induced analgesic, followed by a small robot that clamps onto the tooth, removing tissue without the need for drilling through laser technology. This procedure is guided and controlled by the dentist from a desk. Professor Spallek collaborates with researchers from four leading institutions in Australia to bring this new vision to life.
Outside of his professional responsibilities, Professor Spallek prioritises his family and serves as a volunteer director for Community Connections Australia. This organisation offers a range of tailored services to individuals living with disabilities. With the support of a management team, their 150 frontline workers assist approximately 300 clients in achieving greater independence in their homes.
-
Targeting chemotherapy resistance in ovarian cancer patients
Dr Alex Cole, from the Centenary Institute’s Centre for Biomedical AI, is now leading the research focused on developing a new treatment to counteract a protein called follistatin (FST), known for making ovarian cancer cells resistant to chemotherapy.
By employing cutting-edge molecular biology and directed evolution techniques, the project aims to create nanobodies—small, precise molecules—that can block FST. If successful, these nanobodies could enhance the effectiveness of chemotherapy and improve ovarian cancer treatment rates.
-
Indigenous Australian health and ear disease
Professor Kelvin Kong feels incredibly fortunate to lead a fulfilling life surrounded by his loved ones. With a demonstrated history of service in the health industry, he brings a wealth of expertise across various sectors including clinical research, medical education, surgery, paediatrics, health policy, and Indigenous education. Kelvin started his university, residing at New College in 1992, which brings him fond memories. Graduating from medicine from the University of NSW, Kelvin continued his studies and became a fellow of the Royal Australasian College of Surgeons (RACS) and Australian Society of Otolaryngology, head & neck Society (ASOHNS).
-
Food and fasting periods as medicine to prevent disease
Professor Leonie Heilbronn is based at the South Australian Health and Medical Research Institute (SAHMRI), where she leads the Obesity and Metabolism laboratory. Her research is at the interface between basic and clinical science. She is internationally recognised for her work in nutritional modulation in humans and has made major contributions to our current understanding of mechanisms underlying conditions such as insulin resistance, particularly inflammation and lipid metabolism. She has also contributed significantly to current concepts of caloric restriction (CR), intermittent fasting (IF) and time restricted eating (TRE) in humans. She has published more than 110 peer reviewed papers in scientific journals and is an Associate Editor of Obesity, and Obesity Research and Clinical Practice.
