NUTRACEUTICAL AND PHARMACOLOGICAL INTERVENTION IN NEUROLOGICAL DISORDERS
Dr Virginie Lam, Research Fellow
Curtin Medical Research Institute, Curtin University &
Perron Institute for Neurological and Translational Science
Perth, Western Australia
RESEARCHER PROFILE
Filmed in Perth, Australia | August 2025
Dr Virginie Lam is a neuroscientist and cerebrovascular biologist with over 15 years of research experience, including more than seven years post-PhD. She co-leads the Neurovascular and Metabolic Diseases Laboratory at the Curtin Medical Research Institute and holds an affiliate appointment at the Perron Institute for Neurological and Translational Science. Her research focuses on the interface between neurovascular health, cognitive function, and therapeutic translation in neurodegenerative disorders.
Dr Lam is the scientific project manager and co-investigator of a Medical Research Future Fund (MRFF)-supported Phase II randomised controlled trial in Alzheimer’s disease. She has led the expansion of this study into a multi-site trial involving centres across Western Australia, Tasmania, South Australia, Queensland, and New South Wales. She also established the trial’s first international collaboration in New Zealand, supporting a trans-Tasman research network across academic, hospital, and clinical trial partners.
Dr Lam has secured over AUD$6 million in competitive research funding as chief investigator, including grants from the MRFF, NHMRC, Raine Foundation, WA Future Health Research and Innovation Fund, and the Bryant Stokes Neurological Research Fund. Her expertise spans clinical trial coordination, human research ethics, neuroimaging, cognitive assessment, and the translation of preclinical findings into early-phase interventions. She has authored more than 70 peer-reviewed publications and currently leads a multidisciplinary team of scientists, clinicians, and research personnel.
She serves on the National Imaging Facility (WA Node) Advisory Board, Curtin University’s human and animal research ethics committee, and multiple NHMRC peer review panels. Dr Lam is actively engaged in research governance and capacity building, having founded and co-chaired several early-to-mid-career researcher (EMCR) committees and national working groups. Her research program continues to inform the development of targeted therapeutic strategies for neurovascular and cognitive disorders through rigorous translational science and cross-sector collaboration.
Source: Supplied
https://orcid.org/0000-0001-8463-645X
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De-prescribing medications in older adults with dementia
Dr. Daniel Hoyle is a Senior Lecturer in Therapeutics and Pharmacy Practice at the School of Pharmacy and Pharmacology, University of Tasmania. He is also an experienced clinical pharmacist with expertise in medication management in older people. Dr. Hoyle’s research interests focus on improving medicine use in older people with dementia.
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Neonatal respiratory trials in sick & preterm newborn infants
Prof Brett J. Manley leads and collaborates on large national and international randomised clinical trials in neonatology. He previously collaborated on 4 randomised trials of nasal high-flow as non-invasive respiratory support for preterm and term infants, all of which were published in N Engl J Med. Recently he led the PLUSS trial of intratracheal budesonide for extremely preterm infants, that recruited in 21 NICUs across 4 countries, the results of which were published in JAMA. PLUSS was awarded the Australian Clinical Trials Alliance Trial of the Year in 2025. Another passion of his is mentoring and supervising early career researchers to undertake their own clinical trials.
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Links investigated between poor sleep and onset of dementia
Watch Samantha Bramich, a PHD candidate at the Wicking Dementia Research and Education Centre, University of Tasmania talk on identify the prevalence of rapid eye movement sleep behaviour disorder (RBD) in Tasmania and how poor sleep contributes to the onset of dementia and other diseases.
