BRAIN AGEING, DEMENTIA AND PSYCHIATRIC DISORDERS
Professor Perminder S. Sachdev AM, MBBS, MD, PhD, FRANZCP, FAAHMS, Scientia Professor of Neuropsychiatry, UNSW Sydney & Co-director of the Centre for Healthy Brain Ageing (CHeBA), UNSW Sydney & Director of the Neuropsychiatric Institute, Prince of Wales Hospital, Sydney, Australia & Co-Director of the Australian Dementia Network (ADNeT) & Director of the Centre for Research Excellence in Vascular Contributions to Dementia (CRE VCD)
RESEARCHER PROFILE
Filmed in Sydney, Australia | May 2026
Professor Perminder Sachdev graduated from the All-India Institute of Medical Sciences, New Delhi, in 1978 and completed his MD in Psychiatry there in 1983. Following time in New Zealand, he relocated to Australia, where he completed psychiatric training and a PhD at UNSW in 1991. His doctoral work examined ethnopsychological concepts in Māori culture. His early research focused on drug-induced movement disorders, including akathisia, tardive dyskinesia and neuroleptic malignant syndrome, while his later work has centred on dementia and pre-dementia syndromes, particularly neuroimaging, biomarkers and risk factors.
Professor Sachdev has held numerous leadership roles, including membership of the DSM-5 Neurocognitive Disorders Work Group, President of the International College of Geriatric Psychoneuropharmacology, and leadership positions within VASCOG, the International Neuropsychiatric Association, and the RANZCP Neuropsychiatry Section. He has also contributed extensively to Alzheimer’s Australia and Tourette syndrome advocacy.
His research interests span neuropsychiatric disorders of ageing, vascular and Alzheimer’s dementia, mild cognitive impairment, brain stimulation therapies, neuroimaging, Tourette syndrome and adult ADHD. In 2012, he co-founded CHeBA and leads major longitudinal studies, including the Sydney Memory and Ageing Study, alongside international consortia such as COSMIC, STROKOG and ICC-Dementia.
His achievements have been widely recognised, including appointment as a Member of the Order of Australia (2011), Fellow of the Australian Academy of Health and Medical Sciences (2015), and recipient of the Ryman Prize (2022) for contributions to ageing research. He has also received the Lishman Oration Award (2024) and a Lifetime Achievement Award (2025).
Professor Sachdev has authored over 1,000 journal articles, multiple books, and a book of poetry.
Source: Supplied
https://orcid.org/0000-0002-3421-4176
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Environmental exposure to function of lung epithelial stem cell biology
Dr Clare Weeden has recently commenced as a Laboratory Head at WEHI in 2025, supported by the CSL Centenary Fellowship.
Dr Weeden specialises in lung epithelial cell biology in the context of homeostasis, inflammation, and lung cancer, particularly in people who don’t smoke. Her work endeavours to understand how past environmental exposures shape the responses of lung cells and the molecular mechanisms underlying this cellular recall, with the aim to develop novel early detection strategies for lung disease.
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Neuroscience, neuropharmacology and exercise science
Dr Jacob Thorstensen is an early-career Assistant Professor in Neuroscience and Physiology in the Faculty of Health Sciences & Medicine at Bond University. He is also an honorary research fellow in The School of Biomedical Sciences at The University of Queensland. His work has unveiled several new neuroscientific mechanisms which have future applications for movement disorders.
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New models of care and value in General Practice
Dr Michael Wright is a GP, health economist and health services researcher. Dr Wright currently works as a portfolio GP, combining clinical practice with strategic appointments (most recently with RACGP, Central and Eastern Sydney Primary Health Network, Avant Mutual the Australian Institute of Health and Welfare) and academic research analysing the effects of current health policy on the quality and performance of primary care.
