NON-INVASIVE TOOLS FOR CVD SCREENING AND MONITORING
Dr Hadi Afsharan,
Research Fellow
University of Western Australia &
Harry Perkins Institute of Medical Research,
Perth, Western Australia
RESEARCHER PROFILE
Filmed in Perth, Australia | November 2025
Dr Hadi Afsharan is a Research Fellow Cardiovascular Science & Diabetes at the Harry Perkins Institute of Medical Research; is a translational research and innovation fellow in medical technologies at The University of Western Australia, holding dual titles as Translational Fellow and Innovation Fellow within UWA’s Medical School and the FHRI (Future Health Research and Innovation) program.
He earned his PhD in Biomedical Engineering from UWA in 2023, with a thesis entitled Development of Polarisation-Sensitive Optical Coherence Tomography for Application in Medical Diagnosis, which introduced a pioneering non-invasive imaging method for detecting hypertension and diabetes by analysing retinal blood vessel wall birefringence with exceptional sensitivity and specificity.
Hadi leads several translational research projects, including AI-based retinal biomarkers for coronary artery disease screening, low-cost imaging technologies for heart disease detection in remote communities, and radar-based non-contact measurement of jugular venous pressure, all supported by over $1.8 million in competitive funding from FHRI and UWA.
Source: Supplied
https://orcid.org/0000-0001-7874-2766
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Infections and other lung diseases using models of human lung tissue grown from stem cells
Dr Rhiannon Werder is a Team Leader at Murdoch Children’s Research Institute leading a multidisciplinary team, combining expertise in stem cell biology and immunology, to develop new therapies for lung diseases. Her research centres around induced pluripotent stem cells to investigate respiratory diseases, spanning acute respiratory infections to chronic lung diseases. Using stem cells, Dr Werder’s team creates models of human lung tissue. With these models, Dr Werder is investigating how human-specific pathogens infect different regions of the lung, the ensuing immune responses, and how the lung repairs itself after infections, especially in people with preexisting lung diseases.
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Mechanisms of resistance to menin inhibitor therapy and Acute Myeloid Leukaemia
Dr Rithin Nedumannil (MBBS, MPH, FRACP, FRCPA) is a PhD candidate at the University of Melbourne, undertaking his doctoral studies in collaboration with the Cambridge Stem Cell Institute (Cambridge, UK) and the Peter MacCallum Cancer Centre (Melbourne, Australia). He is a clinical haematologist and haematopathologist with current appointments at Peter MacCallum Cancer Centre, the Royal Melbourne Hospital, Austin Health and Northern Health.
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Neonatal respiratory trials in sick & preterm newborn infants
Prof Brett J. Manley leads and collaborates on large national and international randomised clinical trials in neonatology. He previously collaborated on 4 randomised trials of nasal high-flow as non-invasive respiratory support for preterm and term infants, all of which were published in N Engl J Med. Recently he led the PLUSS trial of intratracheal budesonide for extremely preterm infants, that recruited in 21 NICUs across 4 countries, the results of which were published in JAMA. PLUSS was awarded the Australian Clinical Trials Alliance Trial of the Year in 2025. Another passion of his is mentoring and supervising early career researchers to undertake their own clinical trials.
