RESEARCHER PROFILE (Filmed November 2023)
Dr Brendan Shannon
Head of Postgraduate Programs
Monash University
Melbourne, Australia
Dr Brendan Shannon is a registered paramedic and Head of Postgraduate Programs and Deputy Head of Department of Paramedicine at Monash University.
Transitioning from 12 years clinical work as a paramedic to academia, Dr. Brendan Shannon understands the importance of research and education in the field of healthcare. He became a paramedic, pursued higher education, and transitioned into academia while still maintaining a clinical workload.
Brendan has balanced clinical and academic experience throughout his career and his research is closely informed by paramedicine practice.
Brendan has a keen research interest in alternative care pathways, non-transport, referral services, paramedic practitioners and community paramedicine. His Doctoral research focused on investigating the experiences of health services when implementing alternative care pathways.
These pathways are designed to deliver care in community settings for populations that are traditionally underserved. The programs examined were found to effectively address complex patients’ needs in community settings.
Dr. Shannon is driven to help people’s lives be better, particularly those who don’t have the privileges as others. His focus is on treating underserved communities with chronic diseases and complex social conditions, who frequently use healthcare services, through community paramedicine programs, as well as patients who frequently utilise healthcare services like the emergency department.
“The intersection of chronic disease and complex social conditions presents a unique challenge in healthcare. Researching programs to increase access to care for underserved patients within the community is a big umbrella term with lots of avenues to explore”, says Dr Shannon.
Apart from research, having a purpose to help others and teaching, Dr Shannon has a passion for restoring old cars nurtured from family influences. He also takes part in amateur martial arts, in particular Brazilian jiu-jitsu.
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Infections and other lung diseases using models of human lung tissue grown from stem cells
Dr Rhiannon Werder is a Team Leader at Murdoch Children’s Research Institute leading a multidisciplinary team, combining expertise in stem cell biology and immunology, to develop new therapies for lung diseases. Her research centres around induced pluripotent stem cells to investigate respiratory diseases, spanning acute respiratory infections to chronic lung diseases. Using stem cells, Dr Werder’s team creates models of human lung tissue. With these models, Dr Werder is investigating how human-specific pathogens infect different regions of the lung, the ensuing immune responses, and how the lung repairs itself after infections, especially in people with preexisting lung diseases.
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Personalised approaches to lung therapy
Dr. Adams’ research focus is on lung cancer, which is the deadliest of all cancers worldwide. He is working towards developing personalised approaches to pinpoint a therapy that is going to be most effective for the person with that disease. Dr. Adams’ research is focusing on chemotherapy and targeted therapy, and he is trying to identify upfront which of those tumours are likely to be resistant to the therapy. He then identifies strategies that will resensitize or increase the sensitivity of the tumour to the standard of care that is targeted therapy or chemotherapy.
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Pancreatic and lung cancers driven by mutations in the cancer gene KRAS
Dr Mara Zeissig is a recently appointed Lab Head within the Tumour Inflammation and Immunotherapy Program at the South Australian immunoGENomics Cancer Institute (SAiGENCI).
Her research focuses on studying immune evasion mechanisms in lung and pancreatic cancers to identify novel ways to increase response to immunotherapy. Her expertise is in genetically engineered mouse models of lung cancer, CRISPR-Cas9 screening technologies and T cell based immunotherapies (e.g Checkpoint inhibitors).
